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ORPHA:507Disease
What it is
A parasitic disease caused by protozoa of the genus Leishmania (>20 pathogenic species), transmitted by the bite of infected female phlebotomine sandflies. Three main syndromes are recognized: visceral (VL), cutaneous (CL; localized and diffuse forms) and mucocutaneous leishmaniasis. Post-kala-azar dermal leishmaniasis (PKDL) is a cutaneous sequela of VL. Most infections remain asymptomatic.
Key facts
- Prevalence
- 1-9 / 1 000 000 (Europe)
- Age of onset
- All ages
- Inheritance
- Not applicable
- Classified as
- Disease
Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.
Signs and symptoms
Very common80–99%
14Common30–79%
7These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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