Rare diseases · Sign or symptom
Abnormal bleeding
Bleeding tendency
HP:0001892
What it means
An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.
This term is kept for historical reasons. If possible, a more exact description of the phenotype (i.e., whether there is a vascular, platelet and coagulation defect) should be attempted.
Rare diseases that can present with this90
Very common80–99%
18- Bernard-Soulier syndrome
- Beta-thalassemia-X-linked thrombocytopenia syndrome
- Congenital factor XI deficiency
- Congenital fibrinogen deficiency
- Familial afibrinogenemia
- Familial dysfibrinogenemia
- Familial hypofibrinogenemia
- Familial thrombocytosis
- Generalized juvenile polyposis/juvenile polyposis coli
- Gray platelet syndrome
- Hereditary mixed polyposis syndrome
- Hermansky-Pudlak syndrome
- Leishmaniasis
- Malakoplakia
- Moderate hemophilia A
- Musculocontractural Ehlers-Danlos syndrome
- Periventricular nodular heterotopia
- SLC35A1-CDG
Common30–79%
24- Acute myelomonocytic leukemia
- Acute promyelocytic leukemia
- Acute radiation syndrome
- Alpha-thalassemia-myelodysplastic syndrome
- Autoimmune lymphoproliferative syndrome
- Bleeding disorder in hemophilia A carriers
- Body skin hyperlaxity due to vitamin K-dependent coagulation factor deficiency
- Chédiak-Higashi syndrome
- Congenital alpha2-antiplasmin deficiency
- Congenital factor II deficiency
- Ebola hemorrhagic fever
- Essential thrombocythemia
- Fetal and neonatal alloimmune thrombocytopenia
- Hepatoportal sclerosis
- Hereditary combined deficiency of vitamin K-dependent clotting factors
- Juvenile polyposis of infancy
- Kaposiform lymphangiomatosis
- Lysinuric protein intolerance
- Marburg hemorrhagic fever
- Noonan syndrome
- Pulmonary arteriovenous malformation
- RFT1-CDG
- Superficial siderosis
- Yellow fever
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Bleeding diathesis · Hemorrhagic diathesis
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.