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ORPHA:36397Disease
Also called Adiposalgia · Adipose tissue rheumatism · Dercum disease · Lipomatosis dolorosa
What it is
A rare disorder of subcutaneous tissue characterized by the development of painful, adipose tissue with multiple subcutaneous lipomas, in association with overweight or obesity.
Key facts
- Age of onset
- Adult
- Inheritance
- Autosomal dominant, Not applicable
- Classified as
- Disease
Signs and symptoms
Common30–79%
13- Abdominal distention
- Abdominal pain
- Abnormal circulating lipid concentration
- Asthenia
- Chronic pain
- Elevated circulating C-reactive protein concentration
- Elevated erythrocyte sedimentation rate
- Increased total hemolytic complement activity
- Overweight
- Painful subcutaneous lipomas
- Sparse axillary hair
- Sparse pubic hair
- Subcutaneous lipoma
Sometimes5–29%
20- Arthritis
- Autoimmunity
- Bruising susceptibility
- Constipation
- Developmental regression
- Diabetes mellitus
- Diarrhea
- Dry skin
and 12 more in this range
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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