Rare diseases · Sign or symptom
Abnormal circulating lipid concentration
HP:0003119
What it means
Any deviation from the normal concentration of a lipid in the blood circulation.
According to CHEBI:18059 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
Rare diseases that can present with this20
Very common80–99%
3Common30–79%
10- Acquired generalized lipodystrophy
- Adiposis dolorosa
- Chronic visceral acid sphingomyelinase deficiency
- Fabry disease
- Griscelli syndrome
- Insulin-resistance syndrome type B
- Lipodystrophy due to peptidic growth factors deficiency
- Overlap myositis
- Primary biliary cholangitis
- TBCK-related encephalopathy-severe hypotonia-craniofacial dysmorphism syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Dyslipidaemia · Dyslipidemia
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.