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Start free with EleplanCaribbean parkinsonism
ORPHA:97355Disease
Also called Atypical parkinsonism in the Caribbean
What it is
Parkinsonism with dementia of Guadeloupe is characterised by symmetrical bradykinesia, predominantly axial rigidity, postural instability with early falls and cognitive decline with prominent features of frontal lobe dysfunction.
Key facts
- Age of onset
- Adult, Elderly
- Classified as
- Disease
Signs and symptoms
Common30–79%
23- Abnormal autonomic nervous system physiology
- Action tremor
- Apraxia
- Autonomic bladder dysfunction
- Cerebral cortical atrophy
- Dementia
- Dystonia
- EMG: myopathic abnormalities
- Frontal lobe dementia
- Hallucinations
- Hypometric saccades
- Midline brain calcifications
- Myoclonus
- Orthostatic hypotension
- Palmomental reflex
- Postural instability
- Progressive gait ataxia
- Pseudobulbar behavioral symptoms
- Sleep abnormality
- T2 hypointense basal ganglia
- Ventriculomegaly
- Vertical supranuclear gaze palsy
- Weakness due to upper motor neuron dysfunction
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Benefit programs to look at
Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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