Thyrotoxic periodic paralysis

What it is

A form of acquired hypokalemic periodic paralysis characterized by a triad of acute flaccid paralysis, hypokalemia, and thyrotoxicosis. These episodes vary in duration, lasting from 2 to 72 hours, and in severity, ranging from paresis to complete paralysis. Attacks are triggered by carbohydrate-rich meals or by strenuous physical activity, followed by a period of rest.

Key facts

Prevalence

1-9 / 1 000 000 (Europe)

Age of onset

Adult

Inheritance

Multigenic/multifactorial, Not applicable

Classified as

Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes

ICD-10 codes

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Benefit programs to look at

Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.

Cross-references