Rare diseases · Sign or symptom
Exercise-induced muscle fatigue
HP:0009020
What it means
An abnormally increased tendency towards muscle fatigue induced by physical exercise.
Rare diseases that can present with this10
Common30–79%
9- Dopamine beta-hydroxylase deficiency
- Glycogen storage disease due to lactate dehydrogenase deficiency
- Glycogen storage disease due to phosphoglycerate kinase 1 deficiency
- Hypokalemic periodic paralysis
- Intellectual disability-hyperkinetic movement-truncal ataxia syndrome
- Multiple acyl-CoA dehydrogenase deficiency
- Partial atrioventricular septal defect
- Pure mitochondrial myopathy
- Thyrotoxic periodic paralysis
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Exercise-induced muscle fatigue
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.