Rare diseases · Sign or symptom
Impotence
Difficulty getting a full erection
HP:0000802
What it means
Inability to develop or maintain an erection of the penis.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this35
Very common80–99%
3Common30–79%
17- Adenohypophysitis
- ATTRV30M amyloidosis
- Fragile X-associated tremor/ataxia syndrome
- Functioning gonadotropic adenoma
- Hereditary ATTR amyloidosis
- HJV or HAMP-related hemochromatosis
- Lambert-Eaton myasthenic syndrome
- Manganese poisoning
- Meningioma
- Multiple endocrine neoplasia type 1
- Non-functioning pituitary adenoma
- Panhypophysitis
- Pituitary apoplexy
- Pituitary deficiency due to empty sella turcica syndrome
- Sheehan syndrome
- Spinocerebellar ataxia type 8
- TSH-secreting pituitary adenoma
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Difficulty getting an erection
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.