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Start free with EleplanPituitary deficiency due to empty sella turcica syndrome
ORPHA:91354Disease
Also called Hypopituitarism due to empty sella turcica syndrome
What it is
A rare pituitary deficiency characterized by herniation of the subarachnoid space into the sella turcica, resulting in flattening of the pituitary gland and endocrine dysfunction. Most common endocrine abnormalities are hyperprolactinemia and growth hormone deficit. Clinical symptoms are highly variable and include headaches, irregular menstruation, galactorrhea, obesity, and visual disturbances, among others.
Key facts
- Age of onset
- Adult, Elderly
- Classified as
- Disease
Signs and symptoms
Sometimes5–29%
12- Abnormality of higher mental function
- Abnormality of the cerebrospinal fluid
- Adrenocorticotropic hormone deficiency
- Autoimmunity
- Decreased response to growth hormone stimulation test
- Hypopituitarism
- Increased circulating prolactin concentration
- Pituitary hypothyroidism
and 4 more in this range
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Benefit programs to look at
Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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