Rare diseases · Sign or symptom
Recurrent otitis media
Recurrent middle ear infection
HP:0000403
What it means
Increased susceptibility to otitis media, as manifested by recurrent episodes of otitis media.
Rare diseases that can present with this47
Very common80–99%
5- Autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome due to TPP2 deficiency
- Blepharophimosis-intellectual disability syndrome, Ohdo type
- Deficiency in anterior pituitary function-variable immunodeficiency syndrome
- Sensorineural deafness with dilated cardiomyopathy
- Smith-Magenis syndrome
Common30–79%
23- 17q24.2microdeletion syndrome
- Activated PI3K-delta syndrome
- Cleft lip/palate
- Dubowitz syndrome
- Emanuel syndrome
- FOXP1 Syndrome
- Hypohidrotic ectodermal dysplasia with immunodeficiency
- Keutel syndrome
- Metaphyseal dysostosis-intellectual disability-conductive deafness syndrome
- Monosomy X syndrome
- Mosaic monosomy X syndrome
- Mowat-Wilson syndrome
- Mowat-Wilson syndrome due to a ZEB2 point mutation
- Mowat-Wilson syndrome due to monosomy 2q22
- Mucolipidosis type III alpha/beta
- Primary ciliary dyskinesia
- Resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta
- Roifman syndrome
- T-B-NK- severe combined immunodeficiency due to adenosine deaminase deficiency
- Turner syndrome
- Turner syndrome due to structural X chromosome anomalies
- Wiedemann-Rautenstrauch syndrome
- Young syndrome
Sometimes5–29%
17- 21q22.11q22.12microdeletion syndrome
- 45,X/46,XY mixed gonadal dysgenesis
- 9p13microdeletion syndrome
- Cleft velum
- Fallot complex-intellectual disability-growth delay syndrome
- Hypohidrotic ectodermal dysplasia
- Intellectual disability-facial dysmorphism-hand anomalies syndrome
- Intellectual disability-seizures-abnormal gait-facial dysmorphism syndrome
and 9 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Frequent otitis media · Multiple episodes of otitis media · Otitis media, recurrent · Recurrent episodes of otitis media · Susceptibility to otitis media
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.