Rare diseases · Sign or symptom
Poor appetite
Decreased appetite
HP:0004396
What it means
A reduced desire to eat.
Rare diseases that can present with this44
Very common80–99%
3Common30–79%
25- Angiostrongyliasis
- Bloom syndrome
- Bronchial neuroendocrine tumor
- Chronic myeloid leukemia
- Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis
- Classic Hodgkin lymphoma
- Congenital fiber-type disproportion myopathy
- Congenital sucrase-isomaltase deficiency
- Ebola hemorrhagic fever
- Familial Mediterranean fever
- Glucagonoma
- GRFoma
- Microscopic polyangiitis
- Necrotizing enterocolitis
- Neuroendocrine neoplasm of appendix
- Neuroendocrine tumor of stomach
- Palmoplantar keratoderma-esophageal carcinoma syndrome
- Pellagra
- Post-transplant lymphoproliferative disease
- PPoma
- Rhabdoid tumor
- SHORT syndrome
- Somatostatinoma
- T-cell based immunotherapy-associated cytokine release syndrome
- VIPoma
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Loss of appetite · No appetite
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.