Rare diseases · Sign or symptom
Pituitary hypothyroidism
Low thyroid gland function due to abnormal pituitary gland
HP:0008245
What it means
A type of hypothyroidism that results from a defect in thyroid-stimulating hormone secretion.
Rare diseases that can present with this28
Very common80–99%
3Common30–79%
15- Adenohypophysitis
- Combined pituitary hormone deficiencies, genetic forms
- Craniopharyngioma
- Meningioma
- Non-acquired panhypopituitarism
- Non-functioning pituitary adenoma
- Obesity due to congenital leptin deficiency
- Obesity due to leptin receptor gene deficiency
- Pallister-Hall syndrome
- Panhypophysitis
- Pituitary apoplexy
- Prolactinoma
- Resistance to thyrotropin-releasing hormone syndrome
- Sheehan syndrome
- Xq21microdeletion syndrome
Sometimes5–29%
8The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Secondary hypothyroidism · Thyroid stimulating hormone deficiency · Thyrotropin deficiency · TSH deficient hypothyroidism
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.