Self-limited epilepsy

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Self-limited epilepsy with centrotemporal spikes

ORPHA:1945Disease

Also called BECRS · BECTS · BRE · Benign epilepsy of childhood with centrotemporal spikes · Benign familial epilepsy of childhood with rolandic spikes · Benign rolandic epilepsy · Centrotemporal epilepsy · Rolandic epilepsy · SeLECTS

What it is

A rare focal childhood epilepsy characterized by seizures involving unilateral facial sensory-motor symptoms, with electroencephalogram (EEG) showing sharp biphasic waves over the rolandic region. It is an age-related epilepsy, with excellent outcome. Self-Limited Epilepsy with CentroTemporal Spikes (SeLECTS) was formerly known as benign Rolandic epilepsy or benign epilepsy with centrotemporal spikes.

Key facts

Prevalence
1-5 / 10 000 (annual incidence, Sweden)
Age of onset
Childhood
Inheritance
Autosomal dominant
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes

GABRG2Disease-causing germline mutation(s)
GRIN2ADisease-causing germline mutation(s)
SRPX2Candidate gene tested

ICD-10 codes

G40.0filed under a broader ICD-10 category — shared with 8 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Benefit programs to look at

Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.

Cross-references

GARD 10287MEDDRA 10070530MESH D019305MONDO 0007295OMIM 117100OMIM 245570UMLS C0376532

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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