Rare diseases · Sign or symptom
Hypotension
Low blood pressure
HP:0002615
What it means
Low Blood Pressure, vascular hypotension.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this91
Very common80–99%
16- 46,XY difference of sex development-adrenal insufficiency due to CYP11A1 deficiency
- AA amyloidosis
- Acute adrenal insufficiency
- Addison disease
- Bacterial toxic-shock syndrome
- Cardiogenic shock
- Carnitine-acylcarnitine translocase deficiency
- Colchicine poisoning
- Congenital isolated ACTH deficiency
- Deficiency in anterior pituitary function-variable immunodeficiency syndrome
- Early-onset familial hypoaldosteronism
- Familial glucocorticoid deficiency
- Familial hypoaldosteronism
- Inherited isolated adrenal insufficiency due to partial CYP11A1 deficiency
- Late-onset isolated ACTH deficiency
- Obesity due to SIM1 deficiency
Common30–79%
27- Acute liver failure
- Adult acute respiratory distress syndrome
- Aggressive systemic mastocytosis
- Alexander disease
- Autosomal dominant hypocalcemia
- Cholera
- Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
- Combined pituitary hormone deficiencies, genetic forms
- Congenital adrenal hyperplasia due to 3-beta-hydroxysteroid dehydrogenase deficiency
- Diffuse cutaneous mastocytosis
- Hemorrhagic fever-renal syndrome
- Hydroxykynureninuria
- Infant botulism
- Inhalational anthrax
- Leptospirosis
- Mercury poisoning
- Non-acquired panhypopituitarism
- Non-functioning pituitary adenoma
- Pituitary apoplexy
- Prolactinoma
- Scrub typhus
- Staphylococcal necrotizing pneumonia
- Systemic capillary leak syndrome
- T-cell based immunotherapy-associated cytokine release syndrome
- Triple A syndrome
- TSH-secreting pituitary adenoma
- Whipple disease
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Arterial hypotension
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.