Sydenham chorea

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Sydenham chorea

ORPHA:306731Particular clinical situation in a disease or syndrome

What it is

A rare acquired autoimmune movement disorder characterized by chorea, hypotonia, and emotional lability. Additional clinical features may include motor impersistence and various neuropsychiatric symptoms. As a major clinical manifestation of acute rheumatic fever (ARF), the disorder typically emerges as a post-infectious complication of a group A streptococcal infection and frequently presents alongside cardiac involvement, such as clinical or subclinical carditis.

Key facts

Age of onset
Adolescent, Adult, Childhood
Classified as
Particular clinical situation in a disease or syndrome

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

ICD-10 codes

I02.0ICD-10 uses a narrower term
I02.9ICD-10 uses a narrower term

Cross-references

GARD 7716MEDDRA 10042732MONDO 0017648UMLS C0152113

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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