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Start free with EleplanSubacute inflammatory demyelinating polyneuropathy
ORPHA:206594Disease
Also called Subacute inflammatory demyelinating polyradiculoneuropathy
What it is
A rare neuroinflammatory disease characterized by muscular weakness with impaired sensation, absent or diminished tendon reflexes and elevated cerebrospinal fluid (CSF) protein content. Subacute inflammatory demyelinating polyneuropathy (SIDP) is an intermediate form between Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP).
Key facts
- Age of onset
- All ages
- Classified as
- Disease
Signs and symptoms
Very common80–99%
5Common30–79%
16- Areflexia
- Axonal loss
- Decreased amplitude of sensory action potentials
- Demyelinating motor neuropathy
- Difficulty climbing stairs
- Diffuse peripheral demyelination
- Elevated erythrocyte sedimentation rate
- Frequent falls
- Functional motor deficit
- Gait disturbance
- Increased total leukocyte count
- Pain
- Peripheral demyelination
- Sensorimotor neuropathy
- Somatic sensory dysfunction
- Symmetric peripheral demyelination
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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