Rare diseases · Sign or symptom
Recurrent upper and lower respiratory tract infections
HP:0200117
What it means
Increased susceptibility to upper and lower respiratory tract infections as manifested by recurrent episodes of upper and lower respiratory tract infections.
Rare diseases that can present with this9
Common30–79%
6- Combined immunodeficiency due to ZAP70 deficiency
- Generalized pseudohypoaldosteronism type 1
- Immunodeficiency due to selective anti-polysaccharide antibody deficiency
- Pallister-Hall syndrome
- T-B-NK+ severe combined immunodeficiency due to complete RAG1/2 deficiency
- T-B-NK+ severe combined immunodeficiency due to DCLRE1C deficiency
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.