Rare diseases · Sign or symptom
Periorbital edema
HP:0100539
What it means
Edema affecting the region situated around the orbit of the eye.
Rare diseases that can present with this19
Common30–79%
6Sometimes5–29%
9- Acute monoblastic/monocytic leukemia
- Idiopathic steroid-resistant nephrotic syndrome
- IgG4-related submandibular gland disease
- Lujo hemorrhagic fever
- Meige disease
- Nasolacrimal duct cyst
- Tumor necrosis factor receptor 1 associated periodic syndrome
- Waldenström macroglobulinemia
and 1 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Periorbital cellulitis · Periorbital oedema
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.