Rare diseases · Sign or symptom

Abnormality of the periorbital region

HP:0000606

What it means

An abnormality of the region situated around the orbit of the eye.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Abnormality of the region around the eye · Abnormality of the region around the eye socket · Anomaly of the periorbital region · Deformity of the periorbital region · Malformation of the periorbital region

Abnormality of the periorbital region

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.