Alopecia universalis

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Alopecia universalis

ORPHA:701Disease

What it is

A disorder of most severe form of alopecia areata, an inflammatory disease of the hair follicle, which is characterized by a complete loss of hair of the scalp and all the hair-bearing areas of the body.

Key facts

Prevalence
1-5 / 10 000 (Europe)
Age of onset
All ages
Inheritance
Autosomal recessive, Multigenic/multifactorial
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Gene

HRDisease-causing germline mutation(s)

ICD-10 codes

L63.1ICD-10 names this disease exactly

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 614MEDDRA 10001767MESH C537055OMIM 104000OMIM 203655OMIM 610753UMLS C0263505

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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