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Start free with EleplanMicrosporidiosis
ORPHA:2552Disease
What it is
A rare parasitic disease characterized by chronic diarrhea leading to severe weight loss caused by microsporidia contamination (most commonly by Encephalitozoon or Enterocytozoon). Contamination can occur through ingesting spores present in water or food or via direct human-to-human contact. Immunodeficient patients (such as individuals with HIV, and patients who have undergone a bone marrow or organ transplant) may be severely affected. These protozoan parasites mainly develop in intestinal cells, but can also be found in adipocytes, epithelial cells and blood cells.
Key facts
- Age of onset
- All ages
- Inheritance
- Not applicable
- Classified as
- Disease
Signs and symptoms
Common30–79%
6Sometimes5–29%
8These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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