Rare diseases · Sign or symptom
Vomiting
Throwing up
HP:0002013
What it means
Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this221
Very common80–99%
15- 46,XY difference of sex development-adrenal insufficiency due to CYP11A1 deficiency
- Beta-ketothiolase deficiency
- Colchicine poisoning
- Cystinosis
- Enteric anendocrinosis
- Hyperinsulinism due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency
- Infantile nephropathic cystinosis
- Inherited isolated adrenal insufficiency due to partial CYP11A1 deficiency
- Isolated complex I deficiency
- Mitochondrial neurogastrointestinal encephalomyopathy
- Neurodegeneration due to 3-hydroxyisobutyryl-CoA hydrolase deficiency
- Pyruvate dehydrogenase E3 deficiency
- Short stature due to GHSR deficiency
- SSR4-CDG
- Systemic primary carnitine deficiency
Common30–79%
65- 13q12.3microdeletion syndrome
- 3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form
- AA amyloidosis
- Acquired aneurysmal subarachnoid hemorrhage
- Acquired methemoglobinemia
- Acute liver failure
- Acute radiation syndrome
- Alobar holoprosencephaly
- Alternating hemiplegia of childhood
- Amoebiasis due to free-living amoebae
- Angiostrongyliasis
- Argininosuccinic aciduria
- Benign paroxysmal torticollis of infancy
- Bohring-Opitz syndrome
- Cholera
- Chylomicron retention disease
- Classical Ehlers-Danlos syndrome
- Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
- Classic galactosemia
- Congenital adrenal hyperplasia due to 3-beta-hydroxysteroid dehydrogenase deficiency
- Congenital hyperinsulinism due to HNF4A deficiency
- Congenital lipoid adrenal hyperplasia due to STAR deficency
- Congenital sucrase-isomaltase deficiency
- Diffuse cutaneous mastocytosis
- Duodenal atresia
- Early-onset familial hypoaldosteronism
- Ebola hemorrhagic fever
- Eosinophilic gastroenteritis
- Epidermolysis bullosa simplex with pyloric atresia
- Esophageal atresia
- Ethylene glycol poisoning
- Familial acute necrotizing encephalopathy
- Familial glucocorticoid deficiency
- Fructose-1,6-bisphosphatase deficiency
- Gaucher disease type 2
- Generalized pseudohypoaldosteronism type 1
- Hemorrhagic fever-renal syndrome
- Hereditary angioedema type 1
- Hereditary arginine vasopressin deficiency
- Hyperammonemia due to N-acetylglutamate synthase deficiency
- Infantile hypotonia-oculomotor anomalies-hyperkinetic movements-developmental delay syndrome
- Inhalational anthrax
- Isolated mesenteric vein thrombosis
- Isovaleric acidemia
- Japanese encephalitis
- Juvenile nephropathic cystinosis
- Krabbe disease
- Lead poisoning
- Listeriosis
- Lujo hemorrhagic fever
- Lysinuric protein intolerance
- Marburg hemorrhagic fever
- Medium chain acyl-CoA dehydrogenase deficiency
- MELAS
- Ménétrier disease
- Methotrexate toxicity
- Methylcobalamin deficiency type cblE
- Microphthalmia-brain atrophy syndrome
- Midline interhemispheric variant of holoprosencephaly
- MPI-CDG
- Myxopapillary ependymoma
- NAD(P)HX dehydratase deficiency
- NMDA receptor encephalitis
- Non-functioning pituitary adenoma
- Pancreatoblastoma
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Emesis
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.