Mantle cell lymphoma

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Mantle cell lymphoma

ORPHA:52416Disease

Also called LCM · MCL · Mantle zone lymphoma

What it is

Mantle cell lymphoma is a rare form of malignant non-Hodgkin lymphoma affecting B lymphocytes in the lymph nodes in a region called the ``mantle zone''.

Key facts

Prevalence
1-9 / 100 000 (Europe)
Age of onset
Adult
Inheritance
Multigenic/multifactorial, Not applicable
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes

ATMDisease-causing somatic mutation(s)
CCND1Disease-causing somatic mutation(s)
IGHDisease-causing somatic mutation(s)

ICD-10 codes

C83.1ICD-10 names this disease exactly

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 6969MEDDRA 10061275MESH D020522MONDO 0018876UMLS C4721414

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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