Rare diseases · Sign or symptom
Absent eyebrow
Failure of development of eyebrows
HP:0002223
What it means
Absence of the eyebrow.
Rare diseases that can present with this22
Very common80–99%
7- Ablepharon macrostomia syndrome
- Alopecia universalis
- Craniosynostosis-anal anomalies-porokeratosis syndrome
- Hidrotic ectodermal dysplasia, Christianson-Fourie type
- Hidrotic ectodermal dysplasia, Halal type
- Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome
- LMNA-related cardiocutaneous progeria syndrome
Common30–79%
9- Combined immunodeficiency-multiple intestinal atresia
- EEM syndrome
- Global developmental delay-alopecia-macrocephaly-facial dysmorphism-structural brain anomalies syndrome
- Ichthyosis follicularis-alopecia-photophobia syndrome
- Johnson neuroectodermal syndrome
- Keratosis follicularis-dwarfism-cerebral atrophy syndrome
- Lethal acantholytic erosive disorder
- Oculocerebrofacial syndrome, Kaufman type
- Pili torti-onychodysplasia syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Absent eyebrows · Agenesis of eyebrows · Aplasia of eyebrows · Loss of eyebrows · Missing eyebrows
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.