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R65

Non-billable

Symptoms and signs specifically associated with systemic inflammation and infection

R65 is the ICD-10-CM code for Symptoms and signs specifically associated with systemic inflammation and infection. It is a non-billable category code — use a more specific child code such as R65.1 for billing.

Status
Header (non-billable)
Chapter
R00-R99
Subcodes
2
Edition
FY2026

R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

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No additional coding notes for this code.

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Frequently asked questions

What is ICD-10 code R65?
R65 is the ICD-10-CM code for "Symptoms and signs specifically associated with systemic inflammation and infection". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Is R65 a billable code?
No — R65 is a non-billable header code. Use a more specific child code (such as R65.1) for billing.
What are the subcodes of R65?
R65 has 2 more specific child codes, including R65.1, R65.2.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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