Rare diseases · Sign or symptom
Wide nose
Broad nose
HP:0000445
What it means
Interalar distance more than two standard deviations above the mean for age, i.e., an apparently increased width of the nasal base and alae.
Rare diseases that can present with this72
Very common80–99%
21- 17p13.3microduplication syndrome
- Acromegaly
- Alazami syndrome
- Autosomal dominant Robinow syndrome
- Baraitser-Winter cerebrofrontofacial syndrome
- Blepharonasofacial malformation syndrome
- Cerebrofaciothoracic dysplasia
- Craniofrontonasal dysplasia-Poland anomaly syndrome
- Craniolenticulosutural dysplasia
- Crisponi syndrome
- Filippi syndrome
- Genitopatellar syndrome
- Hydrocephaly-low insertion umbilicus syndrome
- Intellectual disability-dysmorphism-hypogonadism-diabetes mellitus syndrome
- Juberg-Hayward syndrome
- Keutel syndrome
- Microtriplication 11q24.1 syndrome
- Orofaciodigital syndrome type 4
- Rhizomelic dysplasia, Patterson-Lowry type
- Somatomammotropinoma
- Trisomy 1q syndrome
Common30–79%
24- 8q21.11microdeletion syndrome
- Carpenter syndrome
- Coffin-Lowry syndrome
- Distal deletion 6p syndrome
- Early-onset seizures-distal limb anomalies-facial dysmorphism-global developmental delay syndrome
- Frontonasal dysplasia-bifid nose-upper limb anomalies syndrome
- Hajdu-Cheney syndrome
- Intellectual disability-short stature-hypertelorism syndrome
- Lissencephaly syndrome, Norman-Roberts type
- Marfanoid habitus-autosomal recessive intellectual disability syndrome
- Microphthalmia with linear skin defects syndrome
- Mietens syndrome
- MOGS-CDG
- Monosomy 22 syndrome
- Mosaic trisomy 8 syndrome
- Nasopalpebral lipoma-coloboma syndrome
- Non-progressive cerebellar ataxia with intellectual disability
- Oculoauriculofrontonasal syndrome
- Short rib-polydactyly syndrome, Verma-Naumoff type
- Short ulna-dysmorphism-hypotonia-intellectual disability syndrome
- Temple-Baraitser syndrome
- Trisomy 17p syndrome
- Zechi-Ceide syndrome
- Zimmermann-Laband syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Increased breadth of nose · Increased nasal breadth · Increased nasal width · Increased width of nose
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.