Rare diseases · Sign or symptom
Truncal obesity
HP:0001956
What it means
Obesity located preferentially in the trunk of the body as opposed to the extremities.
Rare diseases that can present with this25
Very common80–99%
8Common30–79%
11- Alström syndrome
- Cushing disease
- Cushing syndrome due to ectopic ACTH secretion
- Deafness-genital anomalies-metacarpal and metatarsal synostosis syndrome
- Macrocephaly-spastic paraplegia-dysmorphism syndrome
- MAN1B1-CDG
- Microcephalic osteodysplastic primordial dwarfism type II
- Polyneuropathy-intellectual disability-acromicria-premature menopause syndrome
- Temple syndrome due to maternal uniparental disomy of chromosome 14
- X-linked intellectual disability-cubitus valgus-dysmorphism syndrome
- Xq27.3q28duplication syndrome
Sometimes5–29%
6The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Centripetal obesity
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.