Rare diseases · Sign or symptom

Severe intrauterine growth retardation

Severe prenatal growth deficiency

HP:0008846

What it means

Intrauterine growth retardation that is 4 or more standard deviations below average, corrected for sex and gestational age.

Rare diseases that can present with this12

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Intrauterine growth retardation, severe

Severe intrauterine growth retardation

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.