Rare diseases · Sign or symptom
Recurrent viral infections
HP:0004429
What it means
Increased susceptibility to viral infections as manifested by recurrent episodes of viral infection.
Rare diseases that can present with this19
Very common80–99%
6- Autosomal dominant severe congenital neutropenia
- Combined immunodeficiency due to CRAC channel dysfunction
- Combined immunodeficiency due to DOCK8 deficiency
- Combined immunodeficiency due to ZAP70 deficiency
- Deficiency in anterior pituitary function-variable immunodeficiency syndrome
- Progeria-short stature-pigmented nevi syndrome
Common30–79%
7- Combined immunodeficiency with facio-oculo-skeletal anomalies
- Encephalitis lethargica
- Hepatic veno-occlusive disease-immunodeficiency syndrome
- Immunodeficiency by defective expression of MHC class II
- PGM3-CDG
- T-B-NK+ severe combined immunodeficiency due to complete RAG1/2 deficiency
- T-B+NK+ severe combined immunodeficiency due to IL-7Ralpha deficiency
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.