Rare diseases · Sign or symptom
Progressive distal muscle weakness
HP:0009063
What it means
Progressively reduced strength of the distal musculature.
Rare diseases that can present with this13
Very common80–99%
4Common30–79%
7- Autosomal recessive distal nebulin myopathy
- Distal myopathy, Tateyama type
- HNRNPA1-related adult-onset distal myopathy
- Mitochondrial trifunctional protein deficiency
- MYH14-related peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome
- Oculopharyngodistal myopathy
- X-linked Charcot-Marie-Tooth disease type 3
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Muscle weakness, distal, progressive · Muscle weakness, progressive, distal
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.