Rare diseases · Sign or symptom
Ocular pain
Eye pain
HP:0200026
What it means
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the eye.
Rare diseases that can present with this31
Very common80–99%
5Common30–79%
11- Atopic keratoconjunctivitis
- Bilateral acute depigmentation of the iris
- Crimean-Congo hemorrhagic fever
- Gelatinous drop-like corneal dystrophy
- Idiopathic panuveitis
- Juvenile nephropathic cystinosis
- Lattice corneal dystrophy type I
- Limbal stem cell deficiency
- Neovascular glaucoma
- Thiel-Behnke corneal dystrophy
- Tubulointerstitial nephritis and uveitis syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.