Rare diseases · Sign or symptom
Myocardial infarction
Heart attack
HP:0001658
What it means
Necrosis of the myocardium caused by an obstruction of the blood supply to the heart and often associated with chest pain, shortness of breath, palpitations, and anxiety as well as characteristic EKG findings and elevation of serum markers including creatine kinase-MB fraction and troponin.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this49
Common30–79%
4Sometimes5–29%
35- Acquired aneurysmal subarachnoid hemorrhage
- Acute adrenal insufficiency
- Acute peripheral arterial occlusion
- Alkaptonuria
- Arterial tortuosity syndrome
- Babesiosis
- Behçet disease
- Catastrophic antiphospholipid syndrome
and 27 more in this range
Rare1–4%
9- Craniopharyngioma
- Ebstein malformation of the tricuspid valve
- Hereditary butyrylcholinesterase deficiency
- MYH9-related syndromic thrombocytopenia
- Primary membranoproliferative glomerulonephritis
- Shiga toxin-associated hemolytic uremic syndrome
- Simple cryoglobulinemia
- Snakebite envenomation
and 1 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: MI
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.