Rare diseases · Sign or symptom
Exercise-induced muscle cramps
Exercise-induced muscle cramping
HP:0003710
What it means
Sudden and involuntary contractions of one or more muscles brought on by physical exertion.
Rare diseases that can present with this10
Common30–79%
5- Autosomal recessive axonal neuropathy with neuromyotonia
- Carnitine palmitoyl transferase II deficiency, severe infantile form
- Glycogen storage disease due to muscle glycogen phosphorylase deficiency
- Glycogen storage disease due to phosphoglycerate mutase deficiency
- Lower motor neuron syndrome with late-adult onset
Sometimes5–29%
5The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Muscle cramps following exercise · Muscle cramps on exercise · Muscle cramps on exertion · Muscle cramps with exertion
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.