Rare diseases · Sign or symptom

Dyspareunia

HP:0030016

What it means

Recurrent or persistent genital pain associated with sexual intercourse.

In females, dyspareunia can develop secondary to medical problems such as vestibulitis, vaginal atrophy, or vaginal infection. It can be either physiologically or psychologically based, or a combination of the two. In males, dyspareunia may be related to conditions of the prepuce, glans penis, penile shaft, testicles, and urethra and prostate gland.

Rare diseases that can present with this12

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Dyspareunia

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.