Rare diseases · Sign or symptom
Dental malocclusion
Bad bite
HP:0000689
What it means
Dental malocclusion refers to an abnormality of the occlusion, or alignment, of the teeth and the way the upper and lower teeth fit together, resulting in overcrowding of teeth or in abnormal bite patterns.
Rare diseases that can present with this50
Very common80–99%
7Common30–79%
19- 7q11.23microduplication syndrome
- Acrootoocular syndrome
- Aneurysm-osteoarthritis syndrome
- Apert syndrome
- Auriculocondylar syndrome
- Focal dermal hypoplasia
- Fraser syndrome
- Hemifacial hyperplasia
- McDonough syndrome
- MOMO syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Oligodontia
- Osteogenesis imperfecta
- Pyle disease
- Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome
- Soft and hard cleft palate
- Treacher-Collins syndrome
- Williams syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Angle class 2 malocclusion · Angle class 3 malocclusion · Bilateral crossbite · Bilateral crossbite malocclusion · Incorrect relation between upper and lower dental arches · Malalignment of upper and lower dental arches · Malocclusion · Malocclusion of teeth
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.