Rare diseases · Sign or symptom
Broad nasal tip
Broad tip of nose
HP:0000455
What it means
Increase in width of the nasal tip.
Nasal tip width is assessed at the anterior junction of the alae and the tip. This is easier in persons with a somewhat squared shape of the nasal tip. This may be best viewed from the inferior aspect of the nose. No objective measures are available. See Bulbous nose for a related term.
Rare diseases that can present with this70
Very common80–99%
21- Acrofrontofacionasal dysostosis
- Acromelic frontonasal dysplasia
- Atkin-Flaitz syndrome
- Autosomal recessive cutis laxa type 2, classic type
- Autosomal recessive distal osteolysis syndrome
- Branchioskeletogenital syndrome
- Craniofrontonasal dysplasia-Poland anomaly syndrome
- Distal Xq28 microduplication syndrome
- Intellectual disability-balding-patella luxation-acromicria syndrome
- KAT6-related intellectual disability-craniofacial anomalies-cardiac defects syndrome
- Müllerian derivatives-lymphangiectasia-polydactyly syndrome
- Multiple epiphyseal dysplasia, Lowry type
- Overgrowth-macrocephaly-facial dysmorphism syndrome
- Potocki-Shaffer syndrome
- Schinzel-Giedion syndrome
- SIX2-related frontonasal dysplasia
- Wilson-Turner syndrome
- Wrinkly skin syndrome
- W syndrome
- X-linked intellectual disability, Siderius type
- Xp22.13p22.2duplication syndrome
Common30–79%
30- 1p21.3microdeletion syndrome
- 1q41q42microdeletion syndrome
- 5q22microdeletion syndrome
- 7q11.23microduplication syndrome
- 8q24.3microdeletion syndrome
- 9q31.1q31.3microdeletion syndrome
- Birk-Barel syndrome
- Brachytelephalangic chondrodysplasia punctata
- Branchio-oculo-facial syndrome
- Camptodactyly syndrome, Guadalajara type 3
- Coffin-Siris syndrome
- Combined immunodeficiency with facio-oculo-skeletal anomalies
- Distal deletion 15q syndrome
- Early-onset epileptic encephalopathy-cortical blindness-intellectual disability-facial dysmorphism syndrome
- Focal dermal hypoplasia
- FOXP1 Syndrome
- Growth delay due to insulin-like growth factor I resistance
- Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome
- Intellectual disability-facial dysmorphism-hand anomalies syndrome
- Monosomy 13q34 syndrome
- Mosaic trisomy 8 syndrome
- Neurodevelopmental delay-seizures-ophthalmic anomalies-osteopenia-cerebellar atrophy syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Orofaciodigital syndrome type 6
- PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome
- Schimke immuno-osseous dysplasia
- Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome
- X-linked intellectual disability, Najm type
- X-linked intellectual disability, Stoll type
Sometimes5–29%
18- Cerebello-oculo-facio-genital syndrome
- CTCF-related neurodevelopmental disorder
- DOORS syndrome
- DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
- Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation
- Floating-Harbor syndrome
- GM1 gangliosidosis
- GM1 gangliosidosis type 1
and 10 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Broad upturned nose · Broad, upturned nose · Increased breadth of nasal tip · Increased breadth of tip of nose · Increased width of nasal tip · Increased width of tip of nose · Nasal tip, broad · Nasal tip, wide
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.