Rare diseases · Sign or symptom
Abnormal thalamic MRI signal intensity
HP:0012696
What it means
A deviation from normal signal on magnetic resonance imaging (MRI) of the thalamus.
Rare diseases that can present with this17
Common30–79%
13- Acute bilirubin encephalopathy
- Acute disseminated encephalomyelitis
- Adenohypophysitis
- Alexander disease type I
- Bickerstaff brainstem encephalitis
- Chronic bilirubin encephalopathy
- Leigh syndrome
- MFF-related encephalopathy due to mitochondrial and peroxisomal fission defect
- Neuroferritinopathy
- Panhypophysitis
- Sandhoff disease, infantile form
- Sensory ataxic neuropathy-dysarthria-ophthalmoparesis syndrome
- Tay-Sachs disease
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Abnormal thalamic MRI signal intensity
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.