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Start free with EleplanMultiple system atrophy, parkinsonian type
ORPHA:98933Clinical subtype
Also called MSA, parkinsonian type · MSA-p
What it is
Multiple system atrophy, parkinsonian type (MSA-p) is a form of multiple system atrophy (MSA) with predominant parkinsonian features (bradykinesia, rigidity, irregular jerky postural tremor, and postural instability).
Key facts
- Prevalence
- 1-9 / 100 000 (Europe)
- Age of onset
- Adult
- Inheritance
- Not applicable
- Classified as
- Clinical subtype
Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.
Signs and symptoms
Common30–79%
24- Abnormal autonomic nervous system physiology
- Abnormal brain FDG positron emission tomography
- Abnormal pyramidal signDiagnostic criterion
- Abnormal rapid eye movement sleep
- Anxiety
- Apathy
- Autonomic bladder dysfunctionDiagnostic criterion
- Autonomic erectile dysfunction
- Axial dystonia
- Bradykinesia
- Central sleep apnea
- Constipation
- Depression
- Female anorgasmia
- Frequent falls
- Orofacial dyskinesia
- Orthostatic hypotension due to autonomic dysfunctionDiagnostic criterion
- Orthostatic syncope
- ParkinsonismDiagnostic criterion
- Postural instability
- Raynaud phenomenon
- Resting tremor
- Rigidity
- StridorDiagnostic criterion
Sometimes5–29%
6These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
Gene
ICD-10 codes
ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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