Rare diseases · Sign or symptom
Xerostomia
Dry mouth
HP:0000217
What it means
Dryness of the mouth due to salivary gland dysfunction.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this34
Very common80–99%
7Common30–79%
13- AGel amyloidosis
- Amyotrophic lateral sclerosis
- Antisynthetase syndrome
- Chronic graft versus host disease
- Diffuse cutaneous systemic sclerosis
- Hereditary acrokeratotic poikiloderma
- Hypohidrotic ectodermal dysplasia
- Idiopathic small fibers neuropathy
- IgG4-related submandibular gland disease
- Intestinal botulism
- Lacrimoauriculodentodigital syndrome
- Mixed connective tissue disease
- Reynolds syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased salivary flow · Dry mouth syndrome · Reduced salivation
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.