Rare diseases · Sign or symptom
Syndactyly
Webbed fingers or toes
HP:0001159
What it means
Webbing or fusion of the fingers or toes, involving soft parts only or including bone structure. Bony fusions are referred to as "bony" syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the fingers or toes in a proximo-distal axis are referred to as "symphalangism".
Syndactyly may be partial or complete. In complete syndactyly, the skin is joined all the way to the fingertip. In partial (incomplete) syndactyly, the skin is only joined part of the distance to the fingertip.
Rare diseases that can present with this35
Common30–79%
11- Cerebrofacioarticular syndrome
- Craniofrontonasal dysplasia-Poland anomaly syndrome
- FBLN1-related developmental delay-central nervous system anomaly-syndactyly syndrome
- Focal dermal hypoplasia
- Grange syndrome
- Mowat-Wilson syndrome
- Orofaciodigital syndrome type 6
- Pelvis-shoulder dysplasia
- Silver-Russell syndrome due to a point mutation
- Silver-Russell syndrome due to maternal uniparental disomy of chromosome 7
- Yunis-Varon syndrome
Sometimes5–29%
17- Bardet-Biedl syndrome
- Developmental delay-facial dysmorphism syndrome due to MED13L deficiency
- Isolated tibial hemimelia
- Lacrimoauriculodentodigital syndrome
- Limb-mammary syndrome
- Methylcobalamin deficiency type cblE
- Mosaic trisomy 16 syndrome
- Mosaic trisomy 3 syndrome
and 9 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.