Rare diseases · Sign or symptom

Sudden loss of visual acuity

HP:0001117

What it means

Severe loss of visual acuity within hours or days. This is characteristic of Leber hereditary optic neuropathy.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Sudden central visual loss · Sudden decrease in vision

Sudden loss of visual acuity

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.