Rare diseases · Sign or symptom
Single umbilical artery
Only one artery in umbilical cord instead of two
HP:0001195
What it means
Single umbilical artery (SUA) is the absence of one of the two umbilical arteries surrounding the fetal bladder and in the fetal umbilical cord.
The umbilical cord normally has two arteries and one vein.
Rare diseases that can present with this22
Common30–79%
8Sometimes5–29%
13- 3C syndrome
- Congenital alveolar capillary dysplasia
- Distal deletion 15q syndrome
- Dyssegmental dysplasia, Silverman-Handmaker type
- Fibulo-ulnar hypoplasia-renal anomalies syndrome
- Hyperphosphatasia-intellectual disability syndrome
- Limb body wall complex
- Mosaic trisomy 16 syndrome
and 5 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: 2 vessel cord · 2 vessel umbilical cord · SUA · Two vessel cord · Two vessel umbilical cord · Two-vessel cord
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.