Caring for someone with this diagnosis? Eleplan keeps diagnoses, medications, documents and every specialist in one plan.
Start free with EleplanDiabetic embryopathy
ORPHA:1926Malformation syndrome
Also called Diabetes-induced teratogenicity
What it is
A rare teratologic disease characterized by a range of congenital anomalies associated with poorly controlled maternal diabetes, frequently including abnormalities of the cardiovascular or central nervous system as well as other organ systems, such as skeletal and craniofacial systems. In addition to embryopathy, uncontrolled maternal diabetes can lead to fetal/neonatal complications (including metabolic, respiratory or delivery complications).
Key facts
- Age of onset
- Antenatal, Neonatal
- Inheritance
- Not applicable
- Classified as
- Malformation syndrome
Signs and symptoms
Very common80–99%
21- Abnormal aortic morphology
- Abnormal cardiovascular system morphology
- Abnormality of the neck
- Abnormality of the pulmonary artery
- Abnormal morphology of female internal genitalia
- Abnormal sacrum morphology
- Aplasia/Hypoplasia affecting the eye
- Aplasia/Hypoplasia of the abdominal wall musculature
- Cleft palate
- Cryptorchidism
- Hydronephrosis
- Microcephaly
- Micropenis
- Microtia
- Posteriorly rotated ears
- Renal hypoplasia/aplasia
- Tetralogy of Fallot
- Transposition of the great arteries
- Ureteral duplication
- Ventricular septal defect
- Vertebral segmentation defect
Common30–79%
10These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
Powered by Eleplan
A rare diagnosis is just the start. Eleplan keeps the whole care plan in one place.
Diagnoses, medications, documents, appointments, and the whole care team — organized and always in sync, so you are not retelling the same story to every new specialist. With Ellie, your AI care assistant, on top of it. Free to start.