Rare diseases · Sign or symptom
Recurrent oral thrush
Chronic oral thrush
HP:0009098
What it means
Chronic accumulation and overgrowth of the fungus Candida albicans on the mucous membranes of the mouth, generally manifested as associated with creamy white lesions on the tongue or inner cheeks, occasionally spreading to the gums, tonsils, palate or oropharynx.
Rare diseases that can present with this10
Common30–79%
4Sometimes5–29%
6- Pneumocystosis
- Selective IgM deficiency
- T-B+NK+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta deficiency
- T-B-NK+ severe combined immunodeficiency due to DCLRE1C deficiency
- T-B+NK- severe combined immunodeficiency due to gamma chain deficiency
- T-cell immunodeficiency with thymic aplasia
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Chronic oral candidiasis · Persistent oral thrush
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.