Rare diseases · Sign or symptom

Recurrent mucocutaneous candidiasis

HP:0002728

What it means

Recurrent or persistent superficial Candida infections of the skin, mucous membranes, and nails.

The most commonly involved Candida species is Candida albicans. Chronic mucocutaneous candidiasis (CMC) is usually confined to the cutaneous surface without systemic dissemination. CMC does not represent a specific disease, but rather a phenotypic feature of several immunologic, endocrinologic, and autoimmune disorders.

Rare diseases that can present with this9

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 2 diseases where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Chronic candidiasis of mucosa, skin and nails · Chronic mucocutaneous candidiasis · Mucocutaneous candidiasis · Persistent mucocutaneous candidiasis

Recurrent mucocutaneous candidiasis

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.