Rare diseases · Sign or symptom
Palmoplantar pustulosis
HP:0100847
What it means
A chronic, relapsing, pustular eruption that is localized to the palms and soles.
There are recurrent and painful eruptions of pustules on the palms and the soles of feet that may resolve with red-brown discoloration.
Rare diseases that can present with this3
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Palmoplantar pustules · Pustulosis of palms and soles · Pustulosis palmaris et plantaris
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.