Rare diseases · Sign or symptom
Nyctalopia
Night blindness
HP:0000662
What it means
Inability to see well at night or in poor light.
Rare diseases that can present with this41
Very common80–99%
11Common30–79%
18- Abetalipoproteinemia
- Adult Refsum disease
- Ataxia with vitamin E deficiency
- Bardet-Biedl syndrome
- Bietti crystalline dystrophy
- Brachydactyly-short stature-retinitis pigmentosa syndrome
- Fuchs endothelial corneal dystrophy
- Late-onset retinal degeneration
- Maternal uniparental disomy of chromosome 4 syndrome
- Pantothenate kinase-associated neurodegeneration
- Posterior column ataxia-retinitis pigmentosa syndrome
- Retinitis pigmentosa
- Severe early-childhood-onset retinal dystrophy
- Sorsby fundus dystrophy
- Usher syndrome type 2
- Visual snow syndrome
- Wagner disease
- Woods-Black-Norbury syndrome
Sometimes5–29%
8The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Difficulties with night vision · Night-blindness · Poor night vision
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.