Necrolytic migratory erythema

What it means

Acral or periorificial lesions that evolve in recurrent crops, with an annular and migratory distribution.

This feature can be a manifestation of glucagonoma and other cancers.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category