Rare diseases · Sign or symptom
Nail dysplasia
Atypical nail growth
HP:0002164
What it means
The presence of developmental dysplasia of the nail.
Rare diseases that can present with this26
Very common80–99%
7Common30–79%
8Sometimes5–29%
10- 45,X/46,XY mixed gonadal dysgenesis
- Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form
- DPM1-CDG
- Limb-mammary syndrome
- Microphthalmia with brain and digit anomalies
- Pectus excavatum-macrocephaly-dysplastic nails syndrome
- Pycnodysostosis
- RNF13-related severe early-onset epileptic encephalopathy
and 2 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Dysplastic nails · Onychodysplasia
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.