Rare diseases · Sign or symptom
Miscarriage
HP:0005268
What it means
A pregnancy that ends at a stage in which the fetus is incapable of surviving on its own, defined as the spontaneous loss of a fetus before the 22th week of pregnancy.
The age at which fetal demise is legally classified asa a miscarriage varies between countries with the US being 20 gestational weeks and the UK being 24 gestational weeks. The HPO chooses the average of these age ranges.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this34
Very common80–99%
5Common30–79%
8- Autosomal dominant centronuclear myopathy
- Catastrophic antiphospholipid syndrome
- Congenital plasminogen activator inhibitor type 1 deficiency
- Dyssegmental dysplasia, Silverman-Handmaker type
- Hydrops fetalis
- Kagami-Ogata syndrome due to paternal uniparental disomy of chromosome 14
- Maternal uniparental disomy of chromosome 6 syndrome
- Northern epilepsy
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Early fetal demise · Early foetal demise · Spontaneous abortion
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.